Featured publications

Androgen exposure impairs neutrophil maturation and function within the infected kidney

February 14, 2024

Hreha TN, Collins CA, Cole EB, Jin RJ, Hunstad DA. Androgen exposure impairs neutrophil maturation and function within the infected kidney. mBio. 2024 Feb 14;15(2):e0317023. doi: 10.1128/mbio.03170-23. Epub 2024 Jan 11. PMID: 38206009; PMCID: PMC10865792.

Sex Differences in Population Dynamics during Formation of Kidney Bacterial Communities by Uropathogenic Escherichia coli

March 17, 2021

McLellan LK, Daugherty AL, Hunstad DA. Sex Differences in Population Dynamics during Formation of Kidney Bacterial Communities by Uropathogenic Escherichia coli. Infect Immun. 2021 Mar 17;89(4):e00716-20. doi: 10.1128/IAI.00716-20. PMID: 33468577; PMCID: PMC8090937.

A host receptor enables type 1 pilus-mediated pathogenesis of Escherichia coli pyelonephritis

January 29, 2021

McLellan LK, McAllaster MR, Kim AS, Tóthová Ľ, Olson PD, Pinkner JS, Daugherty AL, Hreha TN, Janetka JW, Fremont DH, Hultgren SJ, Virgin HW, Hunstad DA. A host receptor enables type 1 pilus-mediated pathogenesis of Escherichia coli pyelonephritis. PLoS Pathog. 2021 Jan 29;17(1):e1009314. doi: 10.1371/journal.ppat.1009314. PMID: 33513212; PMCID: PMC7875428.

Androgen-Influenced Polarization of Activin A-Producing Macrophages Accompanies Post-pyelonephritic Renal Scarring

July 28, 2020

Hreha TN, Collins CA, Daugherty AL, Griffith JM, Hruska KA, Hunstad DA. Androgen-Influenced Polarization of Activin A-Producing Macrophages Accompanies Post-pyelonephritic Renal Scarring. Front Immunol. 2020 Jul 28;11:1641. doi: 10.3389/fimmu.2020.01641. PMID: 32849562; PMCID: PMC7399094.

TGFβ1 orchestrates renal fibrosis following Escherichia coli pyelonephritis

March 1, 2020

Hreha TN, Collins CA, Daugherty AL, Twentyman J, Paluri N, Hunstad DA. TGFβ1 orchestrates renal fibrosis following Escherichia coli pyelonephritis. Physiol Rep. 2020 Mar;8(6):e14401. doi: 10.14814/phy2.14401. PMID: 32227630; PMCID: PMC7104652.

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